AIMC Topic: Antithyroid Agents

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Atomic Ga Site Enables Photonanozymes with Specific Inhibition Modes for Primary Drug Screening.

Analytical chemistry Jun 10, 2025
Enzyme inhibition plays a crucial role in drug discovery by governing interactions between molecules and distinct enzymatic sites, facilitating the identification of early drug candidates. However, most nanozymes have been limited to single active si...
Humans Drug Evaluation, Preclinical Enzyme Inhibitors Catalytic Domain Nitriles Antithyroid Agents
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Machine Learning Prediction of Pancreatitis Risk With Antithyroid Drugs: A Nationwide Retrospective Observational Study.

The Journal of clinical endocrinology and metabolism Jun 17, 2025
BACKGROUND: In recent years, there has been increasing data showing that the risk of acute pancreatitis (AP) is increased in patients using methimazole (MMI). The aim of this population-based study was to investigate the association between drugs use...
Humans Machine Learning Prognosis Retrospective Studies Female Risk Factors Aged Young Adult Adult Male Middle Aged Adolescent Hyperthyroidism Pancreatitis Propranolol Antithyroid Agents Propylthiouracil Methimazole
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Data-Driven Strategies for Carbimazole Titration: Exploring Machine Learning Solutions in Hyperthyroidism Control.

The Journal of clinical endocrinology and metabolism Mar 17, 2025
BACKGROUND: University Hospitals Dorset (UHD) has more than 1000 thyroid patient contacts annually. These are primarily patients with autoimmune hyperthyroidism treated with carbimazole titration. Dose adjustments are made by a healthcare professiona...
Humans Machine Learning Algorithms Female Aged Young Adult Adult Male Middle Aged Thyroid Function Tests Carbimazole Hyperthyroidism Antithyroid Agents
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