AIMC Topic: RNA, Circular

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NGCICM: A Novel Deep Learning-Based Method for Predicting circRNA-miRNA Interactions.

IEEE/ACM transactions on computational biology and bioinformatics Oct 9, 2023
The circRNAs and miRNAs play an important role in the development of human diseases, and they can be widely used as biomarkers of diseases for disease diagnosis. In particular, circRNAs can act as sponge adsorbers for miRNAs and act together in certa...
Biomarkers Deep Learning Humans Algorithms MicroRNAs RNA, Circular ROC Curve Computational Biology
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DeepCIP: A multimodal deep learning method for the prediction of internal ribosome entry sites of circRNAs.

Computers in biology and medicine Aug 1, 2023
Circular RNAs (circRNAs) have been found to have the ability to encode proteins through internal ribosome entry sites (IRESs), which are essential RNA regulatory elements for cap-independent translation. Identification of IRES elements in circRNA is ...
Deep Learning RNA, Circular RNA Internal Ribosome Entry Sites
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Predicting CircRNA-Disease Associations via Feature Convolution Learning With Heterogeneous Graph Attention Network.

IEEE journal of biomedical and health informatics Jun 5, 2023
Exploring the relationship between circular RNA (circRNA) and disease is beneficial for revealing the mechanisms of disease pathogenesis. However, a blind search for all possible associations between circRNAs and diseases through biological experimen...
Neural Networks, Computer Algorithms Humans Computational Biology RNA, Circular Forecasting
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CircSSNN: circRNA-binding site prediction via sequence self-attention neural networks with pre-normalization.

BMC bioinformatics May 30, 2023
BACKGROUND: Circular RNAs (circRNAs) play a significant role in some diseases by acting as transcription templates. Therefore, analyzing the interaction mechanism between circRNA and RNA-binding proteins (RBPs) has far-reaching implications for the p...
RNA-Binding Proteins Binding Sites RNA, Circular Neural Networks, Computer Computational Biology
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CRBP-HFEF: Prediction of RBP-Binding Sites on circRNAs Based on Hierarchical Feature Expansion and Fusion.

Interdisciplinary sciences, computational life sciences May 26, 2023
Circular RNAs (circRNAs) participate in the regulation of biological processes by binding to specific proteins and thus influence transcriptional processes. In recent years, circRNAs have become an emerging hotspot in RNA research. Due to powerful le...
RNA Binding Sites RNA-Binding Proteins RNA, Circular Neural Networks, Computer
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Convolution Neural Networks Using Deep Matrix Factorization for Predicting Circrna-Disease Association.

IEEE/ACM transactions on computational biology and bioinformatics Feb 3, 2023
CircRNAs have a stable structure, which gives them a higher tolerance to nucleases. Therefore, the properties of circular RNAs are beneficial in disease diagnosis. However, there are few known associations between circRNAs and disease. Biological exp...
RNA, Circular Neural Networks, Computer Computational Biology
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IGNSCDA: Predicting CircRNA-Disease Associations Based on Improved Graph Convolutional Network and Negative Sampling.

IEEE/ACM transactions on computational biology and bioinformatics Dec 8, 2022
Accumulating evidences have shown that circRNA plays an important role in human diseases. It can be used as potential biomarker for diagnose and treatment of disease. Although some computational methods have been proposed to predict circRNA-disease a...
Computational Biology Neural Networks, Computer RNA, Circular Humans Algorithms
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A web server for identifying circRNA-RBP variable-length binding sites based on stacked generalization ensemble deep learning network.

Methods (San Diego, Calif.) Jul 8, 2022
Circular RNA (circRNA) can exert biological functions by interacting with RNA-binding protein (RBP), and some deep learning-based methods have been developed to predict RBP binding sites on circRNA. However, most of these methods identify circRNA-RBP...
Deep Learning RNA-Binding Proteins Binding Sites RNA, Circular Algorithms
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Prediction of circRNA-Disease Associations Based on the Combination of Multi-Head Graph Attention Network and Graph Convolutional Network.

Biomolecules Jul 2, 2022
Circular RNAs (circRNAs) are covalently closed single-stranded RNA molecules, which have many biological functions. Previous experiments have shown that circRNAs are involved in numerous biological processes, especially regulatory functions. It has a...
RNA, Circular Algorithms RNA Computational Biology Humans Neural Networks, Computer
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CRBPDL: Identification of circRNA-RBP interaction sites using an ensemble neural network approach.

PLoS computational biology Jan 20, 2022
Circular RNAs (circRNAs) are non-coding RNAs with a special circular structure produced formed by the reverse splicing mechanism. Increasing evidence shows that circular RNAs can directly bind to RNA-binding proteins (RBP) and play an important role ...
RNA Splicing Animals RNA, Circular Machine Learning Computational Biology Algorithms Binding Sites RNA-Binding Proteins Neural Networks, Computer Models, Biological
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