BACKGROUND: RNA methylation (RM) regulates gene expression regulation, RNA stability, and protein translation. Accurate prediction of RM modification sites is essential for understanding their biological functions. However, existing wet-lab detection...
With the recent advanced direct RNA sequencing technique that proposed by the Oxford Nanopore Technologies, RNA modifications can be detected and profiled in a simple and straightforward manner. Majority nanopore-based modification studies were devot...
International journal of molecular sciences
Mar 1, 2024
RNA modification plays a crucial role in cellular regulation. However, traditional high-throughput sequencing methods for elucidating their functional mechanisms are time-consuming and labor-intensive, despite extensive research. Moreover, existing m...
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