AIMC Topic: Skin Irritancy Tests

Clear Filters Showing 1 to 2 of 2 articles

Development of an artificial neural network model for risk assessment of skin sensitization using human cell line activation test, direct peptide reactivity assay, KeratinoSens™ and in silico structure alert parameter.

Journal of applied toxicology : JAT Dec 10, 2017
It is important to predict the potential of cosmetic ingredients to cause skin sensitization, and in accordance with the European Union cosmetic directive for the replacement of animal tests, several in vitro tests based on the adverse outcome pathwa...
Humans Neural Networks, Computer Computer Simulation Animals Risk Assessment Mice Lymph Nodes Cell Line Skin Skin Irritancy Tests Dermatitis, Allergic Contact
View on PubMed DOI

In silico risk assessment for skin sensitization using artificial neural network analysis.

The Journal of toxicological sciences Apr 1, 2015
The sensitizing potential of chemicals is usually identified and characterized using in vivo methods such as the murine local lymph node assay (LLNA). Due to regulatory constraints and ethical concerns, alternatives to animal testing are needed to pr...
Neural Networks, Computer Computer Simulation Animals Risk Assessment Mice Predictive Value of Tests Local Lymph Node Assay Skin Irritancy Tests
View on PubMed DOI
Popular Topics
Recent Journals