AIMC Topic: THP-1 Cells

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Machine Learning Enables Live Label-Free Phenotypic Screening in Three Dimensions.

Assay and drug development technologies Jan 1, 2018
There is a large amount of information in brightfield images that was previously inaccessible by using traditional microscopy techniques. This information can now be exploited by using machine-learning approaches for both image segmentation and the c...
Humans Machine Learning Cells, Cultured Phenotype Drug Discovery Antineoplastic Agents Imaging, Three-Dimensional Cell Proliferation Particle Size Cell Differentiation THP-1 Cells Surface Properties Leukemia
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[Optimization and evaluation of an inflammatory cell model in LPS-stimulated PMA-differentiated THP-1 cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Nov 1, 2017
Objective To develop an optimal inflammatory cell model from lipopolysaccharide (LPS)-stimulated phorbol ester (PMA)-differentiated THP-1 cells, and investigate its response to anti-inflammatory agent phosphodiesterase inhibitor rolipram. Methods THP...
Humans Tumor Necrosis Factor-alpha Macrophages Interleukin-6 Lipopolysaccharides Cell Differentiation Anti-Inflammatory Agents Models, Biological THP-1 Cells Inflammation Mediators Tetradecanoylphorbol Acetate Leukemia, Monocytic, Acute Phosphodiesterase 4 Inhibitors Rolipram
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