AIMC Topic: Tosyl Compounds

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Identification of genes related to the effects of bicalutamide and zoladex on benign prostatic hyperplasia.

Scientific reports
Existing research indicates that bicalutamide and zoladex show significant potential in treating prostate cancer. However, in the clinical application of treating benign prostatic hyperplasia (BPH), it is limited due to relatively severe side effects...

Data-Driven Modeling of the Bicalutamide Dissolution from Powder Systems.

AAPS PharmSciTech
Low solubility of active pharmaceutical compounds (APIs) remains an important challenge in dosage form development process. In the manuscript, empirical models were developed and analyzed in order to predict dissolution of bicalutamide (BCL) from sol...