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Vocabulary, Controlled

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Toward a unified understanding of drug-drug interactions: mapping Japanese drug codes to RxNorm concepts.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: Linking information on Japanese pharmaceutical products to global knowledge bases (KBs) would enhance international collaborative research and yield valuable insights. However, public access to mappings of Japanese pharmaceutical products...

Interpretive Description in Computerized Ontology Development: Rigour.

Studies in health technology and informatics
This poster presents the use of Interpretive Description in ontology development. The methods selected attended to the need for quality and rigour.

Special supplement issue on quality assurance and enrichment of biological and biomedical ontologies and terminologies.

BMC medical informatics and decision making
Ontologies and terminologies serve as the backbone of knowledge representation in biomedical domains, facilitating data integration, interoperability, and semantic understanding across diverse applications. However, the quality assurance and enrichme...

Term Candidate Generation to Enrich Clinical Terminologies with Large Language Models.

Studies in health technology and informatics
Annotated language resources derived from clinical routine documentation form an intriguing asset for secondary use case scenarios. In this investigation, we report on how such a resource can be leveraged to identify additional term candidates for a ...

Beyond Tokens: Fair Evaluation of French Large Language Models for Clinical Named Entity Recognition.

Studies in health technology and informatics
Named Entity Recognition (NER) models based on Transformers have gained prominence for their impressive performance in various languages and domains. This work delves into the often-overlooked aspect of entity-level metrics and exposes significant di...

Active Learning Pipeline to Identify Candidate Terms for a CDSS Ontology.

Studies in health technology and informatics
Ontology is essential for achieving health information and information technology application interoperability in the biomedical fields and beyond. Traditionally, ontology construction is carried out manually by human domain experts (HDE). Here, we e...

Knowledge Base Prototype Creating with Using Interdisciplinary Metathesaurus.

Studies in health technology and informatics
This article presents our experience in development an ontological model can be used in clinical decision support systems (CDSS) creating. We have used the largest international biomedical terminological metathesaurus the Unified Medical Language Sys...

Building a Natural Language Interface for FHIR Clinical Terminology Server.

Studies in health technology and informatics
While Fast Healthcare Interoperability Resources (FHIR) clinical terminology server enables quick and easy search and retrieval of coded medical data, it still has some drawbacks. When searching, any typographical errors, variations in word forms, or...

Fine-tuning large language models for rare disease concept normalization.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: We aim to develop a novel method for rare disease concept normalization by fine-tuning Llama 2, an open-source large language model (LLM), using a domain-specific corpus sourced from the Human Phenotype Ontology (HPO).

Annotating publicly-available samples and studies using interpretable modeling of unstructured metadata.

Briefings in bioinformatics
Reusing massive collections of publicly available biomedical data can significantly impact knowledge discovery. However, these public samples and studies are typically described using unstructured plain text, hindering the findability and further reu...