AI Medical Compendium Topic

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Volume Electron Microscopy

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Automated large volume sample preparation for vEM.

Methods in cell biology
New developments in electron microscopy technology, improved efficiency of detectors, and artificial intelligence applications for data analysis over the past decade have increased the use of volume electron microscopy (vEM) in the life sciences fiel...

Instance segmentation of mitochondria in electron microscopy images with a generalist deep learning model trained on a diverse dataset.

Cell systems
Mitochondria are extremely pleomorphic organelles. Automatically annotating each one accurately and precisely in any 2D or volume electron microscopy (EM) image is an unsolved computational challenge. Current deep learning-based approaches train mode...

Deep learning-enhanced automated mitochondrial segmentation in FIB-SEM images using an entropy-weighted ensemble approach.

PloS one
Mitochondria are intracellular organelles that act as powerhouses by breaking down nutrition molecules to produce adenosine triphosphate (ATP) as cellular fuel. They have their own genetic material called mitochondrial DNA. Alterations in mitochondri...

Automated segmentation of cell organelles in volume electron microscopy using deep learning.

Microscopy research and technique
Recent advances in computing power triggered the use of artificial intelligence in image analysis in life sciences. To train these algorithms, a large enough set of certified labeled data is required. The trained neural network is then capable of pro...