Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Aug 12, 2025
Accurate risk stratification is crucial for determining the optimal treatment plan for patients with colorectal cancer (CRC). However, existing deep learning models perform poorly in the preoperative diagnosis of CRC and exhibit limited generalizabil... read more
BACKGROUND: Understanding how genes regulate each other in cells is crucial for determining cell identity and development, and single-cell sequencing technologies facilitate such research through gene regulatory networks (GRNs). However, identifying ... read more
This paper presents the design and fabrication of a compact underdriven bionic frog robot, which is inspired by the locomotion stance of a frog. The robot's hind legs were ingeniously built using an underdriven associative 8-bar linkage mechanism wit... read more
BACKGROUND: As a typical type of neurodegenerative disorders, Parkinson's disease(PD) is characterized by significant clinical and progression heterogeneity. Based on gene expression data, reliable detection of PACE subtypes in Parkinson's disease(PD... read more
Pain is a multifaceted phenomenon that significantly affects a large portion of the global population. Objective pain assessment is essential for developing effective management strategies, which in turn contribute to more efficient and responsive he... read more
This study developed and validated a machine learning (ML) model to predict in-hospital cardiac mortality in 18,727 atrial fibrillation (AF) patients using electronic medical record data. Four ML algorithms-random forest, extreme gradient boosting (X... read more
Rolling bearings are a crucial component in rotating machinery, essential for ensuring the smooth functioning of the entire system. However, their vulnerability to damage necessitates the implementation of effective fault diagnosis. Traditional deep ... read more
Growing energy storage demand has solidified the dominance of lithium-ion batteries (LIBs) in modern societies but intensifies recycling pressures. Precise state-of-health (SOH) assessment is crucial to grouping retired batteries from an unknown stat... read more
N-methyl-D-aspartate receptors (NMDARs) are critical mediators of excitatory neurotransmission and are composed of seven subunits (GluN1, GluN2A-D, and GluN3A-B) that form diverse receptor subtypes. While GluN1/GluN2 subtypes have been extensively ch... read more
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