Differential plasma cytokine variation following X-ray or proton brain irradiation using machine-learning approaches.
Journal:
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
PMID:
39307604
Abstract
PURPOSE: X-ray and proton irradiation have been reported to induce distinct modifications in cytokine expression in vitro and in vivo, suggesting a dissimilar inflammatory response between X-rays and protons. We aimed to investigate the differences in cytokine profiles early following fractionated brain irradiation with X-rays or protons and their relationship with leukocyte subpopulations in rodents.