AIMC Topic: Cranial Irradiation

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Differential plasma cytokine variation following X-ray or proton brain irradiation using machine-learning approaches.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
PURPOSE: X-ray and proton irradiation have been reported to induce distinct modifications in cytokine expression in vitro and in vivo, suggesting a dissimilar inflammatory response between X-rays and protons. We aimed to investigate the differences i...

Predicting overall survival and prophylactic cranial irradiation benefit in small-cell lung cancer with CT-based deep learning: A retrospective multicenter study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: To develop a computed tomography (CT)-based deep learning model to predict overall survival (OS) among small-cell lung cancer (SCLC) patients and identify patients who could benefit from prophylactic cranial irradiation (PCI) ...

Feasibility of automated planning for whole-brain radiation therapy using deep learning.

Journal of applied clinical medical physics
PURPOSE: The purpose of this study was to develop automated planning for whole-brain radiation therapy (WBRT) using a U-net-based deep-learning model for predicting the multileaf collimator (MLC) shape bypassing the contouring processes.

Prediction of Cranial Radiotherapy Treatment in Pediatric Acute Lymphoblastic Leukemia Patients Using Machine Learning: A Case Study at MAHAK Hospital.

Asian Pacific journal of cancer prevention : APJCP
BACKGROUND: Acute Lymphoblastic Leukemia (ALL) is the most common blood disease in children and is responsible for the most deaths amongst children. Due to major improvements in the treatment protocols in the 50-years period, the survivability of thi...

Vector-model-supported optimization in volumetric-modulated arc stereotactic radiotherapy planning for brain metastasis.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Long planning time in volumetric-modulated arc stereotactic radiotherapy (VMA-SRT) cases can limit its clinical efficiency and use. A vector model could retrieve previously successful radiotherapy cases that share various common anatomic features wit...

Early prediction of radiotherapy-induced parotid shrinkage and toxicity based on CT radiomics and fuzzy classification.

Artificial intelligence in medicine
MOTIVATION: Patients under radiotherapy for head-and-neck cancer often suffer of long-term xerostomia, and/or consistent shrinkage of parotid glands. In order to avoid these drawbacks, adaptive therapy can be planned for patients at risk, if the pred...

Intracranial stereotactic radiosurgery with an adapted linear accelerator vs. robotic radiosurgery: Comparison of dosimetric treatment plan quality.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
BACKGROUND AND PURPOSE: Stereotactic radiosurgery with an adapted linear accelerator (linac-SRS) is an established therapy option for brain metastases, benign brain tumors, and arteriovenous malformations. We intended to investigate whether the dosim...

Whole-brain radiotherapy associated with structural changes resembling aging as determined by anatomic surface-based deep learning.

Neuro-oncology
BACKGROUND: Brain metastases are the most common intracranial tumors in adults and are associated with significant morbidity and mortality. Whole-brain radiotherapy (WBRT) is used frequently in patients for palliation, but can result in neurocognitiv...