Repeatability of Microperimetry in Areas of Retinal Pigment Epithelium and Photoreceptor Loss in Geographic Atrophy Supported by Artificial Intelligence-Based Optical Coherence Tomography Biomarker Quantification.

Journal: American journal of ophthalmology
PMID: 39547308

Abstract

PURPOSE: Growing interest in microperimetry (MP) or fundus-controlled perimetry as a targeted psychometric testing method in geographic atrophy (GA) is warranted because of the disease subclinical/extrafoveal appearance or preexisting foveal loss with visual acuity becoming unreliable. We provide comprehensive pointwise test-retest repeatability reference values on the most widely used MP devices and combine them with targeted testing in areas of retinal pigment epithelium (RPE) as well as photoreceptor (PR) integrity loss, guiding the interpretation of sensitivity loss during the long-term follow-up of patients with GA.

Authors

  • Leonard M Coulibaly
    From the Department of Ophthalmology and Optometry (L.M.C., K.B., A.Z., P.F., U.S-E., G.S.R.), Medical University of Vienna, Vienna, Austria.
  • Klaudia Birner
    Laboratory for Ophthalmic Image Analysis, Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
  • Azin Zarghami
    From the Department of Ophthalmology and Optometry (L.M.C., K.B., A.Z., P.F., U.S-E., G.S.R.), Medical University of Vienna, Vienna, Austria.
  • Markus Gumpinger
    Laboratory for Ophthalmic Image Analysis (OPTIMA), Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
  • Simon Schurer-Waldheim
  • Philipp Fuchs
    Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
  • Hrvoje Bogunović
    Christian Doppler Laboratory for Ophthalmic Image Analysis (OPTIMA), Department of Ophthalmology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria.
  • Ursula Schmidt-Erfurth
    Christian Doppler Laboratory for Ophthalmic Image Analysis (OPTIMA), Department of Ophthalmology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria.
  • Gregor S Reiter
    Department of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. gregor.reiter@meduniwien.ac.at.

Keywords

External Resources

Popular Topics
Recent Journals