AIMC Topic: Photoreceptor Cells, Vertebrate
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Repeatability of Microperimetry in Areas of Retinal Pigment Epithelium and Photoreceptor Loss in Geographic Atrophy Supported by Artificial Intelligence-Based Optical Coherence Tomography Biomarker Quantification.
American journal of ophthalmology
Nov 14, 2024
PURPOSE: Growing interest in microperimetry (MP) or fundus-controlled perimetry as a targeted psychometric testing method in geographic atrophy (GA) is warranted because of the disease subclinical/extrafoveal appearance or preexisting foveal loss wit...
Disease Activity and Therapeutic Response to Pegcetacoplan for Geographic Atrophy Identified by Deep Learning-Based Analysis of OCT.
Ophthalmology
Aug 14, 2024
PURPOSE: To quantify morphological changes of the photoreceptors (PRs) and retinal pigment epithelium (RPE) layers under pegcetacoplan therapy in geographic atrophy (GA) using deep learning-based analysis of OCT images.
Label-free imaging flow cytometry for analysis and sorting of enzymatically dissociated tissues.
Scientific reports
Jan 19, 2022
Biomedical research relies on identification and isolation of specific cell types using molecular biomarkers and sorting methods such as fluorescence or magnetic activated cell sorting. Labelling processes potentially alter the cells' properties and ...
Automated detection of preserved photoreceptor on optical coherence tomography in choroideremia based on machine learning.
Journal of biophotonics
Feb 9, 2018
Optical coherence tomography (OCT) can demonstrate early deterioration of the photoreceptor integrity caused by inherited retinal degeneration diseases (IRDs). A machine learning method based on random forests was developed to automatically detect co...
Use of a Machine Learning-Based High Content Analysis Approach to Identify Photoreceptor Neurite Promoting Molecules.
Advances in experimental medicine and biology
Jan 1, 2016
High content analysis (HCA) has become a leading methodology in phenotypic drug discovery efforts. Typical HCA workflows include imaging cells using an automated microscope and analyzing the data using algorithms designed to quantify one or more spec...
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