Evaluation and failure analysis of four commercial deep learning-based autosegmentation software for abdominal organs at risk.

Journal: Journal of applied clinical medical physics
PMID:

Abstract

PURPOSE: Deep learning-based segmentation of organs-at-risk (OAR) is emerging to become mainstream in clinical practice because of the superior performance over atlas and model-based autocontouring methods. While several commercial deep learning-based autosegmentation solutions are now available, the implementation of these tools is still at such a primitive stage that acceptance criteria are underdeveloped due to a lack of knowledge about the systems' segmentation tendencies and failure modes. As the starting point of the iterative process of clinical implementation, this study focuses on the outlier analysis of four commercial autocontouring tools for the abdominal OARs.

Authors

  • Mingdong Fan
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Tonghe Wang
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322.
  • Yang Lei
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322.
  • Pretesh R Patel
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Sean Dresser
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, 30322, USA.
  • Beth Bradshaw Ghavidel
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Richard L J Qiu
    Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, United States of America.
  • Jun Zhou
    Department of Clinical Research Center, Dazhou Central Hospital, Dazhou 635000, China.
  • Kirk Luca
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Oluwatosin Kayode
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
  • Jeffrey D Bradley
    Department of Radiation Oncology, Washington University School of Medicine, Saint Louis, Missouri.
  • Xiaofeng Yang
    Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
  • Justin Roper
    Radiology Oncology, Emory University, 1365 Clifton Road, Department of Radiation Oncology, Atlanta, Atlanta, Georgia, 30322, UNITED STATES.