Study on the mechanism of action of the active ingredient of Calculus Bovis in the treatment of sepsis by integrating single-cell sequencing and machine learning.

Journal: Medicine

PMID: 40258762

Abstract

BACKGROUND: Sepsis, a complex inflammatory condition with high mortality rates, lacks effective treatments. This study explores the therapeutic mechanisms of Calculus Bovis in sepsis using network pharmacology and RNA sequencing.

Authors

Hao Wang

Department of Cardiology, Second Medical Center, Chinese PLA General Hospital, Beijing, China.
Yingchun Hu

Department of Emergency Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China. huyingchun913@swmu.edu.cn.
Li Hu

CAS Key Laboratory of Mental Health, Institute of Psychology (CAS) Beijing, China.

Keywords

China Drugs, Chinese Herbal Humans Machine Learning Molecular Docking Simulation Molecular Dynamics Simulation Network Pharmacology Protein Interaction Maps Sepsis Sequence Analysis, RNA Single-Cell Analysis

External Resources

View on PubMed Access via DOI PubMed (40258762)

Study on the mechanism of action of the active ingredient of Calculus Bovis in the treatment of sepsis by integrating single-cell sequencing and machine learning.

Abstract

Authors

Keywords

External Resources

Popular Topics

Recent Journals