High density of TCF1+ stem-like tumor-infiltrating lymphocytes is associated with favorable disease-specific survival in NSCLC.

Journal: Frontiers in immunology
PMID: 39749327

Abstract

INTRODUCTION: Tumor-infiltrating lymphocytes are both prognostic and predictive biomarkers for immunotherapy response. However, less is known about the survival benefits oftheir subpopulations.

Authors

  • Dagny Førde
    Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
  • Thomas Kilvær
    Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
  • Mona Irene Pedersen
    Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
  • Egil S Blix
    Department of Oncology, University Hospital of North Norway, Tromsø, Norway.
  • Ilona Urbarova
    Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
  • Erna-Elise Paulsen
    Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
  • Mehrdad Rakaee
    Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.
  • Lill-Tove Rasmussen Busund
    Department of Medical Biology, UiT The Arctic University of Norway, Tromsø, Norway.
  • Tom Donnem
    Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
  • Sigve Andersen
    Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

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