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Hepatocyte Nuclear Factor 1-alpha

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High density of TCF1+ stem-like tumor-infiltrating lymphocytes is associated with favorable disease-specific survival in NSCLC.

Frontiers in immunology 39749327
INTRODUCTION: Tumor-infiltrating lymphocytes are both prognostic and predictive biomarkers for immunotherapy response. However, less is known about the survival benefits oftheir subpopulations.
Aged Biomarkers, Tumor Carcinoma, Non-Small-Cell Lung CD8-Positive T-Lymphocytes Female Hepatocyte Nuclear Factor 1-alpha Humans Lung Neoplasms Lymphocytes, Tumor-Infiltrating Male Middle Aged Prognosis
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Unsupervised Clustering of Missense Variants in HNF1A Using Multidimensional Functional Data Aids Clinical Interpretation.

American journal of human genetics 32910913
Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), increase type 2 diabetes ris...
Adolescent Adult Alleles Child Cluster Analysis Datasets as Topic Diabetes Mellitus, Type 2 Exome Sequencing Female Gene Expression Genetic Predisposition to Disease Hepatocyte Nuclear Factor 1-alpha Humans Male Mutation, Missense Norway Phenotype Principal Component Analysis Registries United Kingdom Unsupervised Machine Learning Young Adult
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