Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.

Journal: Renal failure
PMID:

Abstract

BACKGROUND: Little is known about acute kidney injury (AKI) and acute kidney disease (AKD) in patients with chronic obstructive pulmonary disease (COPD) and COPD mortality based on the acute/subacute renal injury. This study develops machine learning models to predict AKI, AKD, and mortality in COPD patients, utilizing web applications for clinical decisions.

Authors

  • Siqi Jiang
    Department of Computer Science, New Jersey Institute of Technology, 323 Dr Martin Luther King Jr Blvd, Newark, NJ 07102, United States.
  • Lingyu Xu
    School of Computer Engineering and Science, Shanghai University, Shanghai, China; Shanghai Institute for Advanced Communication and Data Science, Shanghai University, Shanghai, China.
  • Xinyuan Wang
    Proteomics and Metabolomics Core Facilities, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Chenyu Li
    Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, College of Life Sciences, Northwest University, Xi'an 710069, China.
  • Chen Guan
    Department of Nephrology, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, 266003, China.
  • Lin Che
    Department of Nephrology, the Affiliated Hospital of Qingdao University, Qingdao, China.
  • Yanfei Wang
    Department of Infectious Diseases, College of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang, China.
  • Xuefei Shen
    Department of Nephrology, The Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Qingdao, 266003, China.
  • Yan Xu
    Department of Nephrology, Suzhou Ninth People's Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.