Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes.

Journal: BMC veterinary research
PMID: 40346594

Abstract

BACKGROUND: In recent years, the use of long-chain polyunsaturated fatty acids (PUFA) ω3 and ω6, as food supplements in livestock has increased due to their beneficial properties related to their antioxidant activity. It has been demonstrated however that a high intake of these substances has prooxidant and cell-damaging effects, especially if their circulating concentrations are unbalanced. Starting from these premises, and taking advantage of previous findings, the present study aimed at defining the optimal circulating concentrations and PUFAs ω3/ω6 ratio, to ensure the antioxidant/oxidant balance in sheep RBCs.

Authors

  • Valeria Pasciu
    Department of Veterinary Medicine, University of Sassari, Sassari, Italy. vpasciu@uniss.it.
  • Maria Nieddu
    Department of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
  • Elena Baralla
    Department of Veterinary Medicine, University of Sassari, Sassari, Italy.
  • Ignacio Contreras-Solís
    Department of Agronomy, Biotechnology and Food, University of Navarre, Pamplona, Spain.
  • Francesca Daniela Sotgiu
    Department of Veterinary Medicine, University of Sassari, Sassari, Italy.
  • Fiammetta Berlinguer
    Department of Veterinary Medicine, University of Sassari, Sassari, Italy.

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