Inflammatory bowel disease (IBD) is a heterogeneous group of disorders characterized primarily by chronic relapsing intestinal inflammation, encompassing Crohn's disease (CD) and ulcerative colitis (UC), affecting individuals across age groups with v...
The escalating global crisis of multidrug-resistant (MDR) bacteria demands innovative strategies that bypass conventional antibiotic limitations. This study introduced a multifunctional Au@CuSe core-shell nanoplatform integrating artificial intellige...
Angewandte Chemie (International ed. in English)
Nov 24, 2025
Polyphenols, particularly catechols, represent a significant class of compounds characterized by their versatile physicochemical and biological properties, sourced from both natural origins and industrial by-products. This review highlights their cri...
Robotic micromanipulation has advanced cellular probing, yet achieving precise, minimally invasive intracellular operations without fluorescent labeling remains challenging. Fluorescent techniques often cause photodamage and cytotoxicity and interfer...
Accurately tracking dynamic state transitions is crucial for modeling and predicting biological outcomes, as it captures heterogeneity of cellular responses. To build a model to predict bacterial infection in single cells, we have monitored in parall...
Pancreatic cancer is one of the most lethal malignancies, largely due to the formidable pathophysiological barriers presented by its tumor microenvironment (TME). These include metabolic stress, such as acidosis and elevated reactive oxygen species; ...
Current colorimetric sensing arrays for antioxidant detection often struggle with discrimination due to cross-reactive signals from individual nanozymes. These signals are typically modulated by external factors such as pH or chromogenic substrates, ...
BACKGROUND: Chronic obstructive pulmonary disease (COPD), mainly caused by cigarette smoke (CS), is a global health concern. Ferroptosis is recognized as a key driver of COPD progression, yet its underlying mechanisms are unclear. This study aimed to...
INTRODUCTION: Retinal vein occlusion (RVO) represents a prevalent cause of vision impairment within retinal vascular diseases. Although hypoperfusion and inflammation are recognized pathogenic contributors, emerging evidence highlights oxidative stre...
Managing inflammation in diabetic chronic wounds remains a major clinical challenge, primarily due to the lack of real-time monitoring techniques. To address this issue, we developed a peptide hydrogel capable of simultaneously monitoring the inflamm...
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