Predicting central lymph node metastasis in papillary thyroid microcarcinoma: a breakthrough with interpretable machine learning.

Journal: Frontiers in endocrinology
Published Date: May 12, 2025

Abstract

OBJECTIVE: To develop and validate an interpretable machine learning (ML) model for the preoperative prediction of central lymph node metastasis (CLNM) in papillary thyroid microcarcinoma (PTMC).

Authors

  • Weijun Zhou
    Orthopaedic Department, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, 32# W. Sec 2, 1st Ring Rd, Qingyang District, Chengdu, 610072, China.
  • Lijuan Li
  • Xiaowen Hao
    Department of Ultrasound, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Lanying Wu
    Department of Ultrasound, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Lifu Liu
    Department of Ultrasound, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Binyu Zheng
    Department of Ultrasound, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Yangzheng Xia
    Department of Ultrasound, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Yong Liu
    Department of Critical care medicine, Shenzhen Hospital, Southern Medical University, Guangdong, Shenzhen, China.

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