Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers.

Journal: Annals of clinical and translational neurology
Published Date:

Abstract

OBJECTIVE: Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk-prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy.

Authors

  • Hengjun Wan
    Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Huaju Tian
    Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Cheng Wu
    Department of Automation, Tsinghua University, Beijing 100084, China. Electronic address: wuc@tsinghua.edu.cn.
  • Yue Zhao
    The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China.
  • Daiying Zhang
    Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Yujie Zheng
    Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Yuan Li
    NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China.
  • Xiaoxia Duan
    Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.