AI-powered evaluation of lung function for diagnosis of interstitial lung disease.

Journal: Thorax
Published Date: Jun 16, 2025

Abstract

BACKGROUND: The diagnosis of interstitial lung disease (ILD) can pose a challenge as the pulmonary function test (PFT) is only minimally affected at the onset. To improve early diagnosis, this study aims to explore the potential of artificial intelligence (AI) software in assisting pulmonologists with PFT interpretation for ILD diagnosis. The software provides an automated description of PFT and disease probabilities computed from an AI model.

Authors

  • Daniela Gompelmann
    Division of Pulmonology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria daniela.gompelmann@meduniwien.ac.at.
  • Maximilian Robert Gysan
    Division of Pulmonology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
  • Paul Desbordes
    Information and Communication Technologies, Electronics and Applied Mathematics (ICTEAM), UCLouvain, Belgium.
  • Julie Maes
    ArtiQ, Leuven, Belgium.
  • Karolien Van Orshoven
    ARTIQ, Leuven, Belgium.
  • Maarten De Vos
    STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics-Department of Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium. maarten.devos@kuleuven.be.
  • Markus Steinwender
    Department of Lung Diseases, Leoben, Austria.
  • Erich Helfenstein
    Lungenpraxis Hirslanden, Klinik St. Anna, Lucerne, Switzerland.
  • Corina Marginean
    Clinic of Pulmonary Disease Tg. Mures, County Clinical Hospital Mures, Targu Mures, Romania.
  • Nicolas Henzi
    Department of lung diseases, Spital Limmattal, Schlieren, Switzerland.
  • Peter Cerkl
    Department of Pulmonology, Landeskrankenhaus Hohenems, Hohenems, Austria.
  • Patrick Heeb
    Pulmonary Medicine and Sleep Medicine Center, Zuercher RehaZentren Clinic Wald, Zuerich, Switzerland.
  • Stephan Keusch
    Lungdocs, Zuerich, Switzerland.
  • Gianluca Calderari
    Studio Pneumologia, Lugano, Switzerland.
  • Paul von Boetticher
    Pulmonology, Ordensklinikum Linz Elisabethinen, Linz, Austria.
  • Bernhard Baumgartner
    Department of lung diseases, Salzkammergut Klinikum Vöcklabruck, Vöcklabruck, Austria.
  • Daiana Stolz
    Clinic of Respiratory Medicine and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Marioara Simon
    Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
  • Helmut Prosch
    Universitätsklinik für Radiologie und Nuklearmedizin, Computational Imaging Research Lab, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich.
  • Wim Janssens
  • Marko Topalovic

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