Deep learning dosiomics for the pretreatment prediction of radiation dermatitis in nasopharyngeal carcinoma patients treated with radiotherapy.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published Date: Aug 1, 2025

Abstract

PURPOSE: To develop a combined dosiomics and deep learning (DL) model for predicting radiation dermatitis (RD) of grade ≥ 2 in patients with nasopharyngeal carcinoma (NPC) after radiation therapy (RT) based on radiation dose distribution.

Authors

  • Ziqing Xiang
    Department of Radiotherapy Center, 1(st) Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, PR China.
  • Xianwen Yu
    ByteDance Inc, Beijing, China.
  • Sunzhong Lin
    Medical Engineering and Equipment Department, 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Dong Wang
    Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Weiqian Huang
    Department of Radiotherapy Center, 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Wen Fu
    Department of Radiotherapy Center, 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Xuanxuan Zhu
    Department of Radiotherapy Center, 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Li Shao
    Department of Radiotherapy Center, 1(st) Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, PR China.
  • Jianping Wu
    Department of Civil Engineering, Tsinghua University, Beijing, 100084, China.
  • Qiao Zheng
  • Yao Ai
    Radiotherapy Center, 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
  • Xujing Yang
    Department of Radiotherapy Center, 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. Electronic address: wzyyysj7979@126.com.
  • Mingrou Guo
    Department of Radiotherapy Center, 1st Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. Electronic address: guomingrou@163.com.
  • Xiance Jin
    Department of Radiation and Medical Oncology, The 1st Affiliated Hospital of Wenzhou Medical University, No.2 Fuxue Lane, Wenzhou, 325000, People's Republic of China.

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