Discovery of novel diagnostic biomarkers of hepatocellular carcinoma associated with immune infiltration.

Journal: Annals of medicine
Published Date:

Abstract

OBJECTIVE: Diagnosis of hepatocellular carcinoma (HCC) remains challenging for clinicians. Machine learning approaches and big data analyses are viable strategies for identifying HCC diagnostic markers.

Authors

  • Qiang Liu
    Blood Transfusion Laboratory, Jiangxi Provincial Blood Center Nanchang 330052, Jiangxi, China.
  • Hua Zhang
    School of Clinical Medicine, Hangzhou Medical College, Hangzhou, China.
  • Heng Xiao
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • Ao Ren
    College of Computer Science, Chongqing University, Chongqing, China. Electronic address: ren.ao@cqu.edu.cn.
  • Ying Cai
    College of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
  • Rui Liao
    Siemens Healthineers, Medical Imaging Technologies, Princeton, NJ, USA.
  • Huarong Yu
    Chongqing Medical University, Chongqing, China.
  • Zhongjun Wu
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
  • ZuoTian Huang
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Department of Hepatobiliary Pancreatic Tumor Center, Chongqing University Cancer Hospital, Chongqing, China. Electronic address: 1351619201@qq.com.