Radiomics-based differentiation of upper urinary tract urothelial and renal cell carcinoma in preoperative computed tomography datasets.

Journal: BMC medical imaging
Published Date:

Abstract

BACKGROUND: To investigate a non-invasive radiomics-based machine learning algorithm to differentiate upper urinary tract urothelial carcinoma (UTUC) from renal cell carcinoma (RCC) prior to surgical intervention.

Authors

  • Julian Marcon
    Department of Urology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. julian.marcon@med.uni-muenchen.de.
  • Philipp Weinhold
    Department of Urology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Mona Rzany
    Department of Urology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
  • Matthias P Fabritius
    Department of Radiology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, Germany.
  • Michael Winkelmann
    Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
  • Alexander Buchner
    Department of Urology, LMU University Hospital, Munich, Germany.
  • Lennert Eismann
    Department of Urology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Jan-Friedrich Jokisch
    Department of Urology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
  • Jozefina Casuscelli
    Department of Urology, LMU University Hospital, Munich, Germany.
  • Gerald B Schulz
    Department of Urology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Thomas Knösel
    From the Department of Radiology (S.G., P.W., S.M., C.C.C., J.R., M.I., P.M.K.), Department of Medicine II (C.S.), and Department of Pathology (T.K.), University Hospital, LMU Munich, Marchioninistr 15, 81377 Munich, Germany; and Radiologie München, Munich, Germany (A.G.).
  • Michael Ingrisch
    Department of Radiology, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Jens Ricke
    Department of Radiology, University Hospital Munich, Germany. Electronic address: jens.ricke@med.uni-muenchen.de.
  • Christian G Stief
    Department of Urology, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.
  • Severin Rodler
    Department of Urology, Klinikum der Universitaet Muenchen, Munich, Germany.
  • Philipp M Kazmierczak
    From the Department of Radiology (S.G., P.W., S.M., C.C.C., J.R., M.I., P.M.K.), Department of Medicine II (C.S.), and Department of Pathology (T.K.), University Hospital, LMU Munich, Marchioninistr 15, 81377 Munich, Germany; and Radiologie München, Munich, Germany (A.G.).