Clinical phenotypes and risk of early hemodynamic deterioration in intermediate-high-risk patients with acute pulmonary embolism.

Journal: Thrombosis research
Published Date: Aug 1, 2025

Abstract

INTRODUCTION: Intermediate-high-risk pulmonary embolism (PE) patients face elevated risks of sudden clinical deterioration in early hours after symptoms onset. We performed a hierarchical cluster analysis among intermediate-high risk PE patients to identify phenotypic subgroups and assess their association with hemodynamic deterioration risk within 48 h of admission.

Authors

  • Marco Zuin
    Dipartimento di Medicina Traslazionale, Università degli Studi, Ferrara - Dipartimento di Scienze Cardio-Toraco-Vascolari e Sanità Pubblica, Università degli Studi, Padova.
  • Gregory Piazza
    Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Massachusetts; Department of Medicine, Brigham and Women's Hospital, Division of Cardiovascular Medicine, Harvard Medical School, Boston, Massachusetts. Electronic address: gpiazza@bwh.harvard.edu.
  • Gianluca Rigatelli
    Interventional Cardiology Unit, Division of Cardiology, S. Maria della Misericordia General Hospital, AULSS 5 Polesana, Rovigo, Italy.
  • Amedeo Bongarzoni
    Department of Cardiology, ASST Santi Paolo e Carlo, University of Milan, 20142 Milano, Italy.
  • Iolanda Enea
    Internal and Emergency Medicine, Maddaloni Hospital, Caserta, Italy.
  • Franco Casazza
    Department of Cardiology, San Carlo Borromeo Hospital, Milano, Italy.
  • Claudio Picariello
    Department of Cardiology, S. Maria della Misericordia Hospital, Rovigo, Italy.
  • Claudio Bilato
    Department of Cardiology, West Vicenza Hospital, Arzignano, Vicenza, Italy.
  • Loris Roncon
    Cardiologia, Casa di Cura Città di Rovigo, Rovigo, Italy.

Keywords

External Resources

Popular Topics
Recent Journals