S. aureus and IgE-mediated diseases: pilot or copilot? A narrative review.

Journal: Expert review of clinical immunology
PMID: 35507006

Abstract

INTRODUCTION: is a major opportunistic pathogen that has been implicated in the pathogenesis of several chronic inflammatory diseases including bronchial asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), chronic spontaneous urticaria (CSU), and atopic dermatitis. can induce the production of both polyclonal and specific IgE that can elicit an inflammatory cascade.

Authors

  • Cecilia Calabrese
    Department of Translational Medical Sciences, Institute of Respiratory Diseases, University of Campania "L. Vanvitelli", Naples, Italy.
  • Veronica Seccia
    Otolaryngology Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, Italy.
  • Corrado Pelaia
    Department of Health Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
  • Francesca Spinelli
    Medical Department, Novartis Farma, Origgio, Italy.
  • Paolo Morini
    Medical Department, Novartis Farma, Origgio, Italy.
  • Andrea Rizzi
    Medical Department, Novartis Farma, Origgio, Italy.
  • Aikaterini Detoraki
    Division of Internal Medicine and Clinical Immunology, Department of Internal Medicine, Clinical Immunology, Clinical Pathology and Infectious Diseases, Azienda Ospedaliera Universitaria Federico II, Naples, Italy.

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