IRMA: Machine learning-based harmonization of F-FDG PET brain scans in multi-center studies.

Journal: European journal of nuclear medicine and molecular imaging
Published Date:

Abstract

PURPOSE: Center-specific effects in PET brain scans arise due to differences in technical and procedural aspects. This restricts the merging of data between centers and introduces source-specific bias.

Authors

  • S S Lövdal
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands. s.s.lovdal@rug.nl.
  • R van Veen
    Bernoulli Institute for Mathematics, Computer Science and Artificial Intelligence, University of Groningen, Groningen, Netherlands.
  • G Carli
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands.
  • R J Renken
    Department of Biomedical Sciences of Cells & Systems, Cognitive Neuroscience Center, University Medical Center Groningen, Groningen, Netherlands.
  • T Shiner
    Cognitive Neurology Unit, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
  • N Bregman
    Cognitive Neurology Unit, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
  • R Orad
    Cognitive Neurology Unit, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
  • D Arnaldi
    Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
  • B Orso
    Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
  • S Morbelli
    Nuclear Medicine Unit, IRCCS Ospedale Policlinico S. Martino, Genoa, Italy.
  • P Mattioli
    Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy.
  • K L Leenders
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands.
  • R Dierckx
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands.
  • S K Meles
    Department of Neurology, University Medical Center Groningen, Groningen, Netherlands.
  • M Biehl
    Bernoulli Institute for Mathematics, Computer Science and Artificial Intelligence, University of Groningen, Groningen, Netherlands.