Neuroimaging and biological markers of different paretic hand outcomes after stroke.

Journal: Journal of neuroengineering and rehabilitation
Published Date: Jul 5, 2025

Abstract

BACKGROUND: Hand dysfunction significantly affects independence after stroke, with outcomes varying across individuals. Exploring biomarkers associated with the paretic hand can improve the prognosis and guide personalized rehabilitation. However, whether biomarkers derived from resting-state fMRI (rs-fMRI) can effectively classify and predict different hand outcomes and their biological mechanisms remain unclear.

Authors

  • Zhujun Wang
    Rehabilitation Medicine Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
  • Manxu Zheng
  • Binke Yuan
    Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, Guangzhou, 510631, China.
  • Yingteng Zhang
    Department of Mathematics, Taizhou University, Taizhou, 225300, China.
  • Wenjun Hong
    Department of Rehabilitation Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China. hwj_rehab@njglyy.com.
  • Chaozheng Tang
    Rehabilitation Medicine Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. tang.mdphd@gmail.com.
  • Wen Wu
    Department of Endocrinology, Guangdong General Hospital, Guangzhou, China.

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