Predicting response to non-invasive brain stimulation in post-stroke upper extremity motor impairment: the importance of neurophysiological and clinical biomarkers.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Published Date: Apr 10, 2025

Abstract

BACKGROUND: Non-invasive brain stimulation (NIBS) is a promising approach to enhance upper extremity motor impairment (UEMI) recovery in post-stroke individuals. However, variability in treatment response poses a significant challenge. Identifying neurophysiological and clinical biomarkers that predict NIBS response could improve personalization and treatment efficacy.

Authors

  • Gabriel Barreto
    Applied Neuroscience Laboratory, Universidade Federal de Pernambuco, Recife, Brazil.
  • André Fonseca
    Center of Mathematics, Computation and Cognition, Universidade Federal do ABC, São Paulo, Brazil.
  • Rhayssa Albuquerque
    Applied Neuroscience Laboratory, Universidade Federal de Pernambuco, Recife, Brazil.
  • Camilla Santos
    Applied Neuroscience Laboratory, Universidade Federal de Pernambuco, Recife, Brazil.
  • Rodrigo Brito
    Applied Neuroscience Laboratory, Universidade Federal de Pernambuco, Recife, Brazil.
  • Daniele Piscitelli
    School of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
  • Maria das Graças Rodrigues de Araújo
    Laboratory of kinesiotherapy and manual therapeutic resources, Universidade Federal de Pernambuco, Recife, Brazil.
  • Katia Monte-Silva
    Physical Therapy Department, Universidade Federal de Pernambuco, Recife, Brazil.

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