Multimodal multiphasic preoperative image-based deep-learning predicts HCC outcomes after curative surgery.

Journal: Hepatology (Baltimore, Md.)
Published Date:

Abstract

BACKGROUND AND AIMS: HCC recurrence frequently occurs after curative surgery. Histological microvascular invasion (MVI) predicts recurrence but cannot provide preoperative prognostication, whereas clinical prediction scores have variable performances.

Authors

  • Rex Wan-Hin Hui
    Department of Medicine, Queen Mary Hospital, Hong Kong, China.
  • Keith Wan-Hang Chiu
    Department of Medical Imaging, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China; Consultant in Radiology, Department of Diagnostic and Interventional Radiology, Queen Elizabeth Hospital, Hong Kong; Honorary Associate Professor of the Department of Diagnostic Radiology, Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong. Electronic address: kwhchiu@hku.hk.
  • I-Cheng Lee
    Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
  • Chenlu Wang
    Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
  • Ho-Ming Cheng
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong.
  • Jianliang Lu
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong.
  • Xianhua Mao
    State Key Laboratory of Genetic Engineering, Human Phenome Institute, and School of Life Sciences, Fudan University, Shanghai, China.
  • Sarah Yu
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong.
  • Lok-Ka Lam
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong.
  • Lung-Yi Mak
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong.
  • Tan-To Cheung
    State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.
  • Nam-Hung Chia
    Department of Surgery, Queen Elizabeth Hospital, Hong Kong.
  • Chin-Cheung Cheung
    Department of Surgery, Tuen Mun Hospital, Hong Kong.
  • Wai-Kuen Kan
    Department of Radiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong.
  • Tiffany Cho-Lam Wong
    State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.
  • Albert Chi-Yan Chan
    State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong.
  • Yi-Hsiang Huang
    Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. yhhuang@vghtpe.gov.tw.
  • Man-Fung Yuen
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong.
  • Philip Leung-Ho Yu
    Department of Mathematics and Information Technology, The Education University of Hong Kong, Hong Kong.
  • Wai-Kay Seto
    Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong; Department of Medicine, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China; Clinical Professor in Gastroenterology and Hepatology, State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong; Assistant Dean (Research), LKS Faculty of Medicine, The University of Hong Kong. Electronic address: wkseto@hku.hk.