A Machine Learning-Based Prognostication Model Enhances Prediction of Early Hepatic Encephalopathy in Patients With Noncancer-Related Cirrhosis: Multicenter Longitudinal Cohort Study in Taiwan.

Journal: JMIR medical informatics
Published Date: Aug 6, 2025

Abstract

BACKGROUND: Hepatic encephalopathy (HE) contributes significantly to mortality among patients with liver cirrhosis. Early prediction of HE is essential for clinical decision-making, yet remains challenging-particularly in noncancer-related cirrhosis due to the unpredictable disease course.

Authors

  • Hsin-Yu Chen
    Department of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
  • Yiu-Hua Cheng
    Department of Family Medicine, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.
  • Wei-Chung Yeh
    Department of Family Medicine, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan.
  • Yi-Chuan Chen
    School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Yi-Wen Tsai
    School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

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