MRI-based radiomics for preoperative T-staging of rectal cancer: a retrospective analysis.

Journal: International journal of colorectal disease
Published Date: Aug 8, 2025

Abstract

PUROPOSE: Preoperative T-staging in rectal cancer is essential for treatment planning, yet conventional MRI shows limited accuracy (~ 60-78). Our study investigates whether radiomic analysis of high-resolution T2-weighted MRI can non-invasively improve staging accuracy through a retrospective evaluation in a real-world surgical cohort.

Authors

  • Vittorio Patanè
    Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy. Vittorio.patane@unicampania.it.
  • Umberto Atripaldi
    Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy.
  • Mario Sansone
    Department of Electrical Engineering and Information Technology (DIETI), University of Naples Federico II, via Claudio 21, 80125 Naples, Italy. Electronic address: mario.sansone@unina.it.
  • Luca Marinelli
  • Sara Del Tufo
    Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy.
  • Gianluca Arrichiello
    Oncology Unit, AORN "S. Anna e S. Sebastiano", Caserta, Italy.
  • Davide Ciardiello
    Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Milan. Electronic address: davide.ciardiello@ieo.it.
  • Francesco Selvaggi
    Department of Advanced Medical and Surgical Sciences, Università Degli Studi Della Campania "Luigi Vanvitelli", Naples, Italy.
  • Erika Martinelli
    Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Piazza Luigi Miraglia 2, 80138, Naples, Italy.
  • Alfonso Reginelli
    Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Napoli, Italy.

Keywords

External Resources

Popular Topics
Recent Journals