Domain Knowledge Inclusive Monotonic Neural Network Guides Patient-Specific Induction of General Anesthesia Dosing.
Journal:
A&A practice
Published Date:
Aug 12, 2025
Abstract
BACKGROUND: Postinduction hypotension is a well-known risk factor for adverse postoperative outcomes. Anesthesiologists estimate anesthetic dosages based on a patient's chart and domain knowledge. Machine learning is increasingly applied in predicting postinduction hypotension, with neural networks providing a robust and accurate approach to model complex relationships. This study aims to use machine learning to suggest anesthetic doses, both generalized to an average patient population and personalized for specific patients, incorporating domain knowledge into the modeling process.
