Exploring the potential relationship between kidney disease index and cognitive dysfunction: a machine learning approach with NHANES data.

Journal: BMC geriatrics
Published Date: Aug 26, 2025

Abstract

OBJECTIVE: This study investigates the relationship between the Kidney Disease Index (KDI) and cognitive function, evaluating its potential as a predictive marker for cognitive impairment in older adults. We also compare the performance of KDI with traditional kidney function markers, including estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR), in predicting cognitive decline.

Authors

  • Tianyi Wang
    College of Physical Education, Qiqihar University, Qiqihar 161000, China.
  • Shuang Tang
    Shandong Qingdao Hospital of Integrated Traditional and Western Medicine, Qingdao, 266002, China.
  • Ruwen Zheng
    Heilongjiang University of Chinese Medicine, Harbin, 150040, China.
  • Lin Wang
    Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.

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