Significant correlation between ferroptosis-associated genes and ulcerative colitis: implications for diagnosis and treatment.

Journal: European journal of medical research
Published Date: Aug 29, 2025

Abstract

BACKGROUND: Ulcerative colitis (UC) is a significant type of inflammatory bowel disease (IBD). Ferroptosis is a type of procedural death that is associated with different types of diseases to various degrees. This study aimed to explore the key ferroptosis-associated genes in UC and assess their potential implications for biological therapy.

Authors

  • Kai Zhang
    Anhui Province Key Laboratory of Respiratory Tumor and Infectious Disease, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
  • Kailing Wang
    Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Chengzhao Weng
    Department of Gastroenterology and Hepatology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
  • Dalong Sun
    Department of Gastroenterology and Hepatology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
  • Miao Ouyang
    School of Mathematics and Statistics, Xiamen University of Technology, Xiamen, 361024, Fujian, China.

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