Associations between the 24-h Activity Daily Cycle and Incident Dementia.

Journal: Medicine and science in sports and exercise
Published Date: May 5, 2025

Abstract

BACKGROUND: Physical activity, sedentary behavior (SB), and sleep all impact the risk of incident dementia, however, engagement in these activities is constrained by the 24-h day. Increasing time spent in one activity necessarily reduces time spent in another, making it difficult to fully understand the implications of current behavioral modification recommendations. This study examines how reallocating time spent among sleep, SB, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA) within a 24-h day impacts dementia risk in older adults.

Authors

  • David A Raichlen
    Human and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, California, USA.
  • Daniel H Aslan
    Human and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, California, USA.
  • M Katherine Sayre
    Department of Anthropology, University of California Santa Barbara, Santa Barbara, California, USA.
  • Anamika Nanda
    Human and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA.
  • Pradyumna K Bharadwaj
    Department of Psychology, University of Arizona, Tucson, Arizona, USA.
  • Madeline Ally
    Department of Psychology, University of Arizona, Tucson, Arizona, USA.
  • Silvio Maltagliati
    Human and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, California, USA.
  • Mark H C Lai
    Department of Psychology, University of Southern California, Los Angeles, California, USA.
  • Rand R Wilcox
    Department of Psychology, University of Southern California, Los Angeles, California, USA.
  • Yann C Klimentidis
  • Gene E Alexander
    Department of Psychology, University of Arizona, Tucson, Arizona, USA.

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