Unsupervised delineation of stratum corneum using reflectance confocal microscopy and spectral clustering.

Journal: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Published Date: May 1, 2017

Abstract

BACKGROUND: Measuring the thickness of the stratum corneum (SC) in vivo is often required in pharmacological, dermatological, and cosmetological studies. Reflectance confocal microscopy (RCM) offers a non-invasive imaging-based approach. However, RCM-based measurements currently rely on purely visual analysis of images, which is time-consuming and suffers from inter-user subjectivity.

Authors

  • A Bozkurt
    Electrical and Computer Engineering Department, Northeastern University, Boston, MA, USA.
  • K Kose
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • C Alessi-Fox
    Caliber Imaging and Diagnostics, Rochester, NY, USA.
  • J G Dy
    Electrical and Computer Engineering Department, Northeastern University, Boston, MA, USA.
  • D H Brooks
    Electrical and Computer Engineering Department, Northeastern University, Boston, MA, USA.
  • M Rajadhyaksha
    Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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