Multi-modal discriminative dictionary learning for Alzheimer's disease and mild cognitive impairment.

Journal: Computer methods and programs in biomedicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: The differentiation of mild cognitive impairment (MCI), which is the prodromal stage of Alzheimer's disease (AD), from normal control (NC) is important as the recent research emphasis on early pre-clinical stage for possible disease abnormality identification, intervention and even possible prevention.

Authors

  • Qing Li
    Department of Internal Medicine, University of Michigan Ann Arbor, MI 48109, USA.
  • Xia Wu
    College of Information Science and Technology, Beijing Normal University, Beijing, China.
  • Lele Xu
    College of Information Science and Technology, Beijing Normal University, Beijing 100875, China. Electronic address: xulelebnu@gmail.com.
  • Kewei Chen
    Banner Alzheimer's Institute, AZ USA.
  • Li Yao
    College of Information Science and Technology, Beijing Normal University, Beijing, China.
  • Rui Li
    Department of Oncology, Xiyuan Hospital, China Academy of Chinese Medical Science, Beijing, China.