The water-soluble subfraction from Artemisia argyi alleviates LPS-induced inflammatory responses via multiple pathways and targets in vitro and in vivo.

Journal: Journal of ethnopharmacology
PMID: 38380576

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE: As a traditional Chinese medicine, Artemisia argyi has been used medicinally and eaten for more than 2000 years in China. It is widely reported in treating inflammatory diseases such as eczema, dermatitis, arthritis, allergic asthma and colitis. Although several studies claim that its volatile oil and organic reagent extracts have certain anti-inflammatory effects, the water-soluble fractions and molecular mechanisms have not been studied.

Authors

  • Le Chen
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: chenle9169@163.com.
  • Yunyun Zhu
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
  • Yuqiao Wang
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan, 430065, China.
  • Zhouyuan Li
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan, 430065, China.
  • Ziling Wang
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
  • Yuhuan Miao
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan, 430065, China.
  • Hongzhi Du
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan, 430065, China. Electronic address: dhz3163@hbtcm.edu.cn.
  • Dahui Liu
    School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan, 430065, China. Electronic address: liudahui@hbtcm.edu.cn.

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