Screening for Alzheimer's Disease Using Saliva: A New Approach Based on Machine Learning and Raman Hyperspectroscopy.

Journal: Journal of Alzheimer's disease : JAD
Published Date: Jan 1, 2019

Abstract

BACKGROUND: Alzheimer's disease and related dementias (ADRDs) are being diagnosed at epidemic rates, with incidence to triple from 35 to 115 million cases worldwide. Most ADRDs are characterized by progressive neurodegeneration, and Alzheimer's disease (AD) is the sixth leading cause of death in the United States. The ideal moment for diagnosing ADRDs is during the earliest stages of its progression; however, current diagnostic methods are inefficient, expensive, and unsuccessful at making diagnoses during the earliest stages of the disease.

Authors

  • Nicole M Ralbovsky
    Department of Chemistry, University at Albany, SUNY, Albany, NY, USA.
  • Lenka Halámková
    Department of Chemistry, University at Albany, SUNY, Albany, NY, USA.
  • Kathryn Wall
    Department of Psychology and Neuroscience, Union College, Schenectady, NY, USA.
  • Cay Anderson-Hanley
    Department of Psychology and Neuroscience, Union College, Schenectady, NY, USA.
  • Igor K Lednev
    Department of Chemistry, University at Albany, SUNY, Albany, NY, USA.

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