Comparative clinical evaluation of atlas and deep-learning-based auto-segmentation of organ structures in liver cancer.

Journal: Radiation oncology (London, England)
Published Date: Nov 27, 2019

Abstract

BACKGROUND: Accurate and standardized descriptions of organs at risk (OARs) are essential in radiation therapy for treatment planning and evaluation. Traditionally, physicians have contoured patient images manually, which, is time-consuming and subject to inter-observer variability. This study aims to a) investigate whether customized, deep-learning-based auto-segmentation could overcome the limitations of manual contouring and b) compare its performance against a typical, atlas-based auto-segmentation method organ structures in liver cancer.

Authors

  • Sang Hee Ahn
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Adam Unjin Yeo
    Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Kwang Hyeon Kim
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Chankyu Kim
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Youngmoon Goh
    Department of Radiation Oncology, Asan Medical Center, Seoul, South Korea.
  • Shinhaeng Cho
    Department of Radiation Oncology, Chonnam National University Medical School, Gwangju, South Korea.
  • Se Byeong Lee
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Young Kyung Lim
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Haksoo Kim
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Dongho Shin
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Taeyoon Kim
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Tae Hyun Kim
    Center for Liver Cancer, National Cancer Center, 111 Jungbalsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-769, Republic of Korea.
  • Sang Hee Youn
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Eun Sang Oh
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea.
  • Jong Hwi Jeong
    Department of Radiation Oncology, Proton Therapy Center, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10408, South Korea. jonghwi@ncc.re.kr.

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