Machine-learning analysis of contrast-enhanced CT radiomics predicts recurrence of hepatocellular carcinoma after resection: A multi-institutional study.

Journal: EBioMedicine
PMID: 31735556

Abstract

BACKGROUND: Current guidelines recommend surgical resection as the first-line option for patients with solitary hepatocellular carcinoma (HCC); unfortunately, postoperative recurrence rate remains high and there is no reliable prediction tool. We explored the potential of radiomics coupled with machine-learning algorithms to improve the predictive accuracy for HCC recurrence.

Authors

  • Gu-Wei Ji
    Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, Nanjing, PR China; NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, PR China. Electronic address: drjgw@njmu.edu.cn.
  • Fei-Peng Zhu
    Department of Radiology, the First Affiliated Hospital with Nanjing Medical University, No. 300, Guangzhou Rd, Nanjing, Jiangsu Province 210009, China.
  • Qing Xu
    Department of Reproductive Medicine, Zigong Hospital of Women and Children Health Care, Zigong, China.
  • Ke Wang
    China Electric Power Research Institute, Haidian District, Beijing 100192, China. wangke1@epri.sgcc.com.cn.
  • Ming-Yu Wu
    Department of Hepatobiliary Surgery, Wuxi People's Hospital, Wuxi, PR China.
  • Wei-Wei Tang
    Department of General Surgery, Nanjing First Hospital, Nanjing, PR China.
  • Xiang-Cheng Li
    Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, Nanjing, PR China; NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, PR China. Electronic address: drxcli@njmu.edu.cn.
  • Xue-Hao Wang
    Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China; Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, Nanjing, PR China; NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, PR China. Electronic address: wangxh@njmu.edu.cn.

Keywords

External Resources

Popular Topics
Recent Journals