Machine-learning-derived rules set excludes risk of Parkinson's disease in patients with olfactory or gustatory symptoms with high accuracy.

Journal: Journal of neurology
Published Date:

Abstract

BACKGROUND: Chemosensory loss is a symptom of Parkinson's disease starting already at preclinical stages. Their appearance without an identifiable etiology therefore indicates a possible early symptom of Parkinson's disease. Supervised machine-learning was used to identify parameters that predict Parkinson's disease among patients having sought medical advice for chemosensory symptoms.

Authors

  • Jörn Lötsch
    Institute of Clinical Pharmacology, Goethe - University, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany.
  • Antje Haehner
    Department of Otorhinolaryngology, Smell and Taste Clinic, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
  • Thomas Hummel
    Smell &Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.