Effect of a deep-learning computer-aided detection system on adenoma detection during colonoscopy (CADe-DB trial): a double-blind randomised study.

Journal: The lancet. Gastroenterology & hepatology
PMID:

Abstract

BACKGROUND: Colonoscopy with computer-aided detection (CADe) has been shown in non-blinded trials to improve detection of colon polyps and adenomas by providing visual alarms during the procedure. We aimed to assess the effectiveness of a CADe system that avoids potential operational bias.

Authors

  • Pu Wang
    Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
  • Xiaogang Liu
    Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China. gary.samsph@gmail.com.
  • Tyler M Berzin
    Beth Israel Deaconess Medical Center and Harvard Medical School, Center for Advanced Endoscopy, Boston , MA, USA.
  • Jeremy R Glissen Brown
    Beth Israel Deaconess Medical Center and Harvard Medical School, Center for Advanced Endoscopy, Boston , MA, USA.
  • Peixi Liu
    Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
  • Chao Zhou
    Department of Electrical and Computer Engineering, Lehigh University, Bethlehem, Pennsylvania.
  • Lei Lei
    Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Liangping Li
    Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
  • Zhenzhen Guo
    School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China.
  • Shan Lei
    Department of Gastroenterology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China.
  • Fei Xiong
    Department of Ultrasound, Deyang People's Hospital, Deyang, Sichuan, China.
  • Han Wang
    Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore.
  • Yan Song
    Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
  • Yan Pan
    Department of Gastroenterology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China.
  • Guanyu Zhou
    Department of Gastroenterology, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China. Electronic address: zhou.guanyu@outlook.com.