Could automated machine-learned MRI grading aid epidemiological studies of lumbar spinal stenosis? Validation within the Wakayama spine study.

Journal: BMC musculoskeletal disorders
Published Date: Mar 12, 2020

Abstract

BACKGROUND: MRI scanning has revolutionized the clinical diagnosis of lumbar spinal stenosis (LSS). However, there is currently no consensus as to how best to classify MRI findings which has hampered the development of robust longitudinal epidemiological studies of the condition. We developed and tested an automated system for grading lumbar spine MRI scans for central LSS for use in epidemiological research.

Authors

  • Yuyu Ishimoto
    MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, UK. yuyu.ishimoto@hotmail.co.jp.
  • Amir Jamaludin
    Department of Engineering Science, University of Oxford, Oxford, UK.
  • Cyrus Cooper
    MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, UK.
  • Karen Walker-Bone
    MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, Hampshire, UK.
  • Hiroshi Yamada
    Toxicogenomics Informatics Project, National Institute of Biomedical Innovation, Health and Nutrition.
  • Hiroshi Hashizume
    Orthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
  • Hiroyuki Oka
    Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical & Research Center, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
  • Sakae Tanaka
    Department of Orthopedic Surgery, Sensory and Motor System Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Noriko Yoshimura
    Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, 113-8655, Japan.
  • Munehito Yoshida
    Orthopedic surgery, Wakayama Medical University, Wakayama city, Wakayama prefecture, Japan.
  • Jill Urban
    Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
  • Timor Kadir
    Mirada Medical, Oxford, UK.
  • Jeremy Fairbank
    Botnar Institute of Musculoskeletal Sciences, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK. jeremy.fairbank@ndorms.ox.ac.uk.

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