Effect of vessel wall segmentation on volumetric and radiomic parameters of coronary plaques with adverse characteristics.

Journal: Journal of cardiovascular computed tomography
Published Date:

Abstract

BACKGROUND: Quantitative coronary plaque parameters are increasingly being utilized as surrogate endpoints of pharmaceutical trials. However, little is known whether differences in segmentation significantly alter parameter values.

Authors

  • Márton Kolossváry
    Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary. Electronic address: marton.kolossvary@cirg.hu.
  • Natasa Jávorszky
    MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, Hungary.
  • Júlia Karády
    From the MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Varosmajor St, 1122 Budapest, Hungary (M.K., J.K., B.M., P.M.H.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (J.K., Y.K., A.I., M.T.L., B.F., H.J.A., U.H.); Center for Cause of Death Investigation, Faculty of Medicine, Hokkaido University, Hokkaido, Japan (Y.K.); Department for Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Freiburg, Germany (C.L.S.); and Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (H.J.A.).
  • Milán Vecsey-Nagy
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
  • Tamás Zoltán Dávid
    MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, Hungary.
  • Judit Simon
    MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, Hungary.
  • Bálint Szilveszter
    MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Városmajor Street, Budapest, Hungary.
  • Béla Merkely
    From the MTA-SE Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, 68 Varosmajor St, 1122 Budapest, Hungary (M.K., J.K., B.M., P.M.H.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (J.K., Y.K., A.I., M.T.L., B.F., H.J.A., U.H.); Center for Cause of Death Investigation, Faculty of Medicine, Hokkaido University, Hokkaido, Japan (Y.K.); Department for Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Freiburg, Germany (C.L.S.); and Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (H.J.A.).
  • Pál Maurovich-Horvat
    Philips Medical Systems Technologies Ltd., Advanced Technologies Center, Haifa, 3100202, Israel.