Identifying sarcopenia in advanced non-small cell lung cancer patients using skeletal muscle CT radiomics and machine learning.

Journal: Thoracic cancer
PMID:

Abstract

BACKGROUND: Sarcopenia has been confirmed as a poor prognostic indicator of lung cancer. However, the lack of abdominal computed tomography (CT) hindered the application to assess the status of sarcopenia. The purpose of this study was to assess the ability of chest CT radiomics combined with machine learning classifiers to identify sarcopenia in advanced non-small cell lung cancer (NSCLC) patients.

Authors

  • Xing Dong
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Xu Dan
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Ao Yawen
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Xu Haibo
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Li Huan
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Tu Mengqi
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Chen Linglong
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Ruan Zhao
    Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.