Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation.

Journal: Journal of medical Internet research
Published Date: Nov 6, 2020

Abstract

BACKGROUND: COVID-19 has infected millions of people worldwide and is responsible for several hundred thousand fatalities. The COVID-19 pandemic has necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods to meet these needs are lacking.

Authors

  • Akhil Vaid
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Sulaiman Somani
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Adam J Russak
    Department of Internal Medicine, Mount Sinai Hospital, New York, NY, USA.
  • Jessica K De Freitas
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave, 15th Fl, New York, NY, 10065, USA.
  • Fayzan F Chaudhry
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ishan Paranjpe
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Kipp W Johnson
  • Samuel J Lee
    Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
  • Riccardo Miotto
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA, and also with the Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.
  • Felix Richter
    Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Shan Zhao
    Department of Mathematics, University of Alabama, Tuscaloosa, AL 35487-0350, USA.
  • Noam D Beckmann
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Nidhi Naik
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Arash Kia
    Department of Mathematics & Statistics, University of Limerick, Limerick, Ireland.
  • Prem Timsina
    Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Anuradha Lala
    Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Manish Paranjpe
    Harvard Medical School, Boston, Massachusetts.
  • Eddye Golden
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Matteo Danieletto
    1Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, NY USA.
  • Manbir Singh
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Dara Meyer
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Paul F O'Reilly
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Laura Huckins
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Patricia Kovatch
  • Joseph Finkelstein
    Department of Biomedical Informatics, School of Medicine, University of Utah, USA.
  • Robert M Freeman
    Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Edgar Argulian
    Department of Cardiology, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Pl, New York, NY 10029, USA.
  • Andrew Kasarskis
  • Bethany Percha
    Program in Biomedical Informatics, Stanford University, Stanford, California, USA.
  • Judith A Aberg
    Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Emilia Bagiella
    Institute for Healthcare Delivery Science, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Carol R Horowitz
    Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Barbara Murphy
    Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Eric J Nestler
    Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Eric E Schadt
    Icahn Institute for Genomics and Multiscale Biology and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Judy H Cho
    The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Carlos Cordon-Cardo
    Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Valentín Fuster
    Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; The Zena and Michael A. Wiener Cardiovascular Institute/Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, New York. Electronic address: vfuster@cnic.es.
  • Dennis S Charney
    Office of the Dean, Icahn School of Medicine of Mount Sinai.
  • David L Reich
    Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Erwin P Bottinger
    Hasso Plattner Institute of Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Matthew A Levin
    Department of Anesthesiology, Perioperative, and Pain Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Pl, New York, NY 10029, USA.
  • Jagat Narula
  • Zahi A Fayad
    Translational and Molecular Imaging Institute (TMII), Icahn School of Medicine at Mount Sinai, Department of Radiology, NY, USA.
  • Allan C Just
    Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Alexander W Charney
    Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Girish N Nadkarni
    Division of Data-Driven and Digital Medicine (D3M), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Benjamin S Glicksberg
    The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave, 15th Fl, New York, NY, 10065, USA.

Keywords

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